Ulkavis of the tab. of p/o of 120 mg No. 112

Tablets "Ulkavis ^® " are applied at the following indications:

• a peptic ulcer of a stomach and duodenum, including the caused Helicobacter pylori (as a part of schemes of antikhelikobakterny therapy);
chronic gastritis also gastroduodenit
• in an aggravation phase, including the caused Helicobacter pylori.

Structure

Active ingredient - bismuth subcitrate (one tablet contains 120 mg of bismuth of oxide in the form of bismuth a dicitrate trikaliya (subcitrate bismuth)).

Excipients: starch corn, K-30 povidone, potassium polakrilin, macrogoal 6000, magnesium stearate; film cover: opadray ІІ transparent (contains: polyvinyl alcohol, macrogoal 4000, talc), titan dioxide (E 171).

Contraindication

• hypersensitivity to active substance or to any excipient;
• heavy renal failure.

Route of administration

to Adults and children is more senior than 14 years to apply on one tablet 4 times a day or two tablets 2 times a day in 30 minutes prior to food and for the night.

on one tablet 2 times a day in 30 minutes prior to food.

to Children aged from the 4th up to 8 years to appoint in a dose 8 mg/kg/days, according to body weight:

• on one tablet a day in 30 minutes prior to food;
to children with body weight more than 30 kg to apply
• on one tablet 2 times a day in 30 minutes prior to food.

Tablet whole, washing down with a small amount of water. Duration of a course of treatment - 4-8 weeks. Within, at least, next 2 months it is not necessary to take the medicaments containing bismuth.

in the presence of Helicobacter pylori in schemes of treatment: at a kvadroterapiya the reception combination "Ulkavis ^® ", tablets on 120 mg 4 times a day with tetracycline of 500 mg 4 times a day, metronidazole of 500 mg 3 times a day and inhibitor of a proton pomp (omeprazolum, lansoprazoly, rabeprazoly, pantoprazoly or esomeprazole) in a standard therapeutic dose 2 times a day is recommended.

Duration of combination therapy - 10-14 days.

For improvement of regeneration of ulcer defect perhaps further medicament treatment "Ulkavis ^® " on one tablet 4 times a day - in 30 minutes prior to a breakfast, a lunch, a dinner and before going to bed. Therapy duration medicament "Ulkavis ^® " - up to 6 weeks (at most - 8 weeks).

Because of insufficiency of data the use during pregnancy and feeding by a breast is not recommended to

Feature of use

.

Children

children can use Drug aged from 4 years.

Drivers

Are not present data on influence of medicament on ability to run vehicles or other mechanisms. However such influence of medicament "Ulkavis ^® " is improbable.

Overdose

Happens in case of frequent reception of high doses of medicament and can be shown in 10 days by the symptoms characteristic of a renal failure (increase in level of bismuth in blood plasma).

in case of a renal failure that is followed by the high content of bismuth in blood plasma, are applied by complexing connections - dimercaptoamber and dimercaptopro-pan-sulfonic acids.

Treatment consists in gastric lavage with the subsequent use of activated carbon and osmotic depletive. Bismuth absorption as additional treatment it is not obligatory. At the accompanying serious illness of kidneys it is necessary to carry out a hemodialysis.

Side effects

from a digestive tract: very often (> 10%) - excrements of black color.

to Store

in original packing for protection against influence of moisture and light, out of children's reach.

Expiration date - 3 years.