Tiara of the Trio of the tab. of p/o 5mg/12.5mg/160mg No. 14

Blocker of receptors of angiotensin II. A tiara of the Trio it is shown to use at treatment of essential hypertensia for adult patients with the arterial blood pressure which is adequately controlled by a combination of an amlodipin, a valsartan and a hydrochlorothiazide which apply in the form of three separate medicines or in the form of two medicines, one of which is combined.

1 tablet of 5 mg / 12.5 mg / 160 mg contains

:

active ingredients: an amlodipina besilat in terms of amlodipin 5 mg of a hydrochlorothiazide of 12.5 mg of a valsartan of 160 mg;

excipients: cellulose microcrystalline, croscarmellose sodium, krospovidon, silicon dioxide colloidal, magnesium stearate, opadray AI 85 F pink.

Contraindication

• sensitivity to active ingredients, other streptocides, derivatives of dihydropyridine or to medicament excipient;
• II and III pregnancy trimester;
• abnormal liver function, biliary cirrhosis or cholestasia;
• heavy renal failures (SKF <30 ml/min. / 1.73 sq.m), an anury and also stay on dialysis;
• simultaneous use the Trio Tiara from the aliskiren-containing means at patients with diabetes or with renal failures (SKF <60 mg/min. / 1.73 sq.m);
• refractory hypopotassemia, hyponatremia, hypercalcemia, symptomatic hyperuricemia;
• heavy hypotension;
• shock (including cardiogenic shock);
• obstruction of an output path of a left ventricle (for example, hypertrophic subaortic stenosis and stenosis of an aorta of heavy degree);
• hemodynamically unstable heart failure after an acute myocardial infarction.

Route of administration

Recommended medicament dose the Trio Tiara - 1 tablet of 5 mg / 12.5 mg / 160 mg a day, are desirable in the morning.

Maximum recommended medicament dose the Trio Tiara - 10 mg / 25 mg / 320 mg.

Use during pregnancy is recommended to

Feature of use

, only if there is no safer alternative medicament and if the disease bears bigger risk for mother and an embryo.

medicine Use the Trio Tiara during feeding by a breast is not recommended to

.

Children

by

therefore medicament is not used to patients of this age group.

Drivers

This medicament does not influence speed of response at control of motor transport or other mechanisms.

Overdose

Is not present data on medicine overdose the Trio Tiara.

Side effects

from digestive tract: often - nausea, vomiting, abdominal discomfort, pain in an upper part of a stomach, infrequently - change of frequency of defecation, diarrhea, dryness in a mouth, dyspepsia very seldom - gastritis, a hyperplasia of gums, pancreatitis.

from a liver and biliary tract: very seldom - hepatitis, an intra hepatic cholestasia, jaundice, increase in level of enzymes of a liver, including increase in level of bilirubin in blood serum (more connected with a cholestasia).

from kidneys and an urinary system: infrequently - urination disturbance, a nocturia, a pollakiuria.

from a metabolism, metabolism: very seldom - a hyperglycemia.

from nervous system: often - dizziness, a headache, drowsiness infrequently - a dysgeusia, paresthesias, a syncope, a tremor, a hypesthesia; very seldom - hypertensia, peripheral neuropathy, neuropathy; frequency is unknown - extrapyramidal symptoms.

from mentality: seldom - a depression, an insomnia / sleep disorder, changes of mood; seldom - confusion.

from heart: often - palpitation; very seldom - arrhythmia (including bradycardia, ventricular tachycardia, fibrillation of auricles), a myocardial infarction.

from vessels: often - rushes of blood infrequently - arterial hypotension very seldom - a vasculitis.

to Store

in original packing at a temperature not above 25 °C, out of children's reach.

Expiration date - 2 years.