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Nitresan of the tab. of 10 mg No. 30

Nitresan of the tab. of 10 mg No. 30
Nitresan of the tab. of 10 mg No. 30
Nitresan of the tab. of 10 mg No. 30
Nitresan of the tab. of 10 mg No. 30
Nitresan of the tab. of 10 mg No. 30
$25.89
Tax $25.89
  • Stock: In Stock
  • Model: 182581

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Description

Tablets "Nitresan ® " are applied to treatment of essential hypertensia.

Structure

Active ingredient - nitrendipin (one tablet contains 10 mg of a nitrendipin).

Excipients: lactoses monohydrate, starch corn, cellulose microcrystalline, magnesium stearate, povidone, sodium docusate.

Contraindication

  • hypersensitivity to a nitrendipin or to other antagonist of calcium of a 1.4-dihydropyridinic row or to any auxiliary component of drug;
  • cardiogenic shock;
  • heavy degree of a stenosis of the aortal valve;
  • unstable stenocardia;
  • an acute myocardial infarction which occurred within the last 4 weeks;
  • a concomitant use with rifampicin.

Route of administration

by

is Appointed inside in the morning after a meal. It is necessary to swallow of tablets entirely, without chewing, washing down with enough water (for example, a glass). It is strictly forbidden to wash down with grapefruit juice.

Active ingredient nitrendipin is sensitive

to light therefore tablets should be taken out from the blister only before use.

One tablet of medicament "Nitresan ® " to accept

two times a day (in the morning and in the evening) that makes 20 mg of a nitrendipin a day. In an insufficient lowering of arterial pressure the doctor at treatment can double a daily dose and to appoint reception of 2 tablets two times a day that is equivalent to a daily dose of 40 mg.

Maximum daily dose - 40 mg.

Dose and the number of receptions is established by the doctor individually. For achievement of the maximum therapeutic effect the individual medicament dosing depending on a condition of the patient, his reaction to medicament and shipping is recommended. Duration of treatment is defined by a clinical condition of the patient.

Sick advanced age and patients with abnormal liver functions

Metabolism of a nitrendipin can slow down that leads to an undesirable lowering of arterial pressure. As the therapeutic effect can be strengthened and/or prolonged, it is recommended to begin treatment with low doses (10 mg of a nitrendipin a day) under observation of the doctor.

to

In cases of a considerable lowering of arterial pressure, even at use of low doses, it is necessary to change treatment.

to

Renal failure

by

to Patients with renal failures easy and moderate severity does not need special correction of doses.

to

Pregnant

to

Drug is contraindicated to

Feature of use

during pregnancy.

Nitrendipin gets into breast milk. In case of need uses of medicament it is necessary to stop feeding by a breast.

Children

do not use Drug to children due to the lack of data on effect of its influence and safe use.

Drivers

In an initiation of treatment or at use of the raised doses, or at combination therapy with other antihypertensive drugs, or at simultaneous alcohol intake is recommended to abstain from control of vehicles and from potentially dangerous types of activity requiring special attention and speed of psychomotor reactions as with a lowering of arterial pressure the attention level can decrease.

Overdose

Symptoms of acute intoxication

Inflows of heat, headache, arterial hypotension (blood circulation collapse), change of heart rate (tachycardia or bradycardia).

Treatment

needs to bring medicament out of an organism: to wash out digestive tract, to accept activated carbon. To make careful observation of a condition of the vital functions of the patient. In a considerable lowering of arterial pressure it is necessary to accept dopamine and noradrenaline. It is necessary to pay attention to potential negative impacts of catecholamines (especially concerning disturbances of a warm rhythm). In bradycardia intravenous administration of atropine or an ortsiprenalin (similarly as at treatment of intoxication other blockers of calcium channels). Perhaps repeated introduction of 10 ml of 10% of calcium of a gluconate or 10% of Calcii chloridum with the subsequent infusion of calcium (it is necessary not to allow at the same time possible development of a hypercalcemia). In such cases also catecholamines, but in higher doses are also effective. Symptomatic further treatment.

Nitrendipin does not give in to dialysis therefore hemoperfusion and a plasmapheresis will not be effective.

Side effects

from the immune system: infrequently - allergic reactions, including skin reactions and allergic hypostases / angiooteki.

from a cardiovascular system: very often - peripheral hypostases (especially in an initiation of treatment, usually fast-passing); often - in an initiation of treatment attacks of stenocardia or increase in frequency, duration and weight of attacks of stenocardia at the patients having this disease are possible; heartbeat, tachycardia; infrequently - arterial hypotension; seldom - a leykotsitoklastichesky vasculitis; very seldom - a myocardial infarction.

from the system of blood and lymphatic system: very seldom - a leukopenia, an agranulocytosis. The composition of peripheral blood was normalized after the termination of administration of drug.

from nervous system: very often - a headache (especially in an initiation of treatment, usually slight and fast-passing); infrequently - uneasiness, sleep disorders, paresthesias, dizziness, fatigue, a tremor (at the raised doses), drowsiness, nervousness, migraine, a hypesthesia.

from organs of sight: infrequently - a disorder of vision, misting of sight.

from organs of hearing and a vestibular mechanism: infrequently - dizziness, sonitus, vertigo.

from a respiratory system: infrequently - short wind, nasal bleeding.

from digestive system: often - feeling of overflow of a stomach; infrequently - nausea, diarrhea, vomiting, an abdominal pain, dryness in a mouth, a constipation, a gastroenteritis; very seldom - a hyperplasia of gums.

from kidneys and urinary tract: infrequently - peripheral hypostases of the lower extremities; seldom - desires to urination; polyuria.

from skin: very often - inflows of heat (especially in an initiation of treatment, usually fast-passing); infrequently - hypersensitivity reactions (itching, urticaria, an erythema, rash, a photosensitization); very seldom - exfoliative dermatitis, a Quincke's disease, makulopapulezny rash.

from a musculoskeletal system: infrequently - an arthralgia myalgia.

from a reproductive system and mammary glands: very seldom - erectile dysfunction, a gynecomastia (at elderly patients), a menorrhagia.

from a liver and biliary tract: seldom - an abnormal liver function, increase in level of separate laboratory indicators (insignificant or moderate increase in transaminases).

Other: infrequently - cold, nonspecific pain, increase in body weight, the increased perspiration; very seldom - fever.

Storage conditions

to Store

in original packing at a temperature not above 25 °C, in the inaccessible for children and protected from light place.

Expiration date - 4 years.

Specifications

Characteristics
Active ingredients Nitrendipin
Amount of active ingredient 10 mg
Applicant Pro.Med.CS
Code of automatic telephone exchange C08CA08 Nitrendipin
Interaction with food Later
Light sensitivity Sensitive
Market status Traditional
Origin Chemical
Prescription status According to the prescription
Primary packing blister
Producer PRAGUE TSS PRO-HONEY
Quantity in packing 30 tablets (3 blisters on 10 pieces)
Release form tablets for internal use
Route of administration Oral
Sign Import
Storage temperature from 5 °C to 25 °C
Trade name Nitresan