Meralis Intensiv nazat spray. solution fl. 10 ml

Spray nasal "Meralis ^® Intensiv" is applied to symptomatic treatment of congestion of a nose and a rhinorrhea at respiratory diseases.

Structure

1 ml of medicine contains (active ingredients):

• a bromide ipratropiya - 0.6 mg;
• xylomethazolinum of a hydrochloride - 0.5 mg.

Excipients: the water sea purified dinatrium edetat, glycerin of 85%, hydrochloric acid and sodium hydroxide (for correction rn), the water purified.

Contraindication

• hypersensitivity to any components of medicine;
• hypersensitivity to atropine or to similar means, for example to Hyoscyaminum, Scopolaminum;
• postponed surgical interventions on a firm cover of a brain, for example transfenoidalny hypophysectomy or other transnasal operations;
• sharp coronary diseases, coronary asthma, hyperthyroidism;
• glaucoma;
• dry rhinitis;
• children's age (up to 18 years).

Route of administration

is Applied intranazalno.

Recommended dose for adults makes on one injection 3 times a day in each nasal course. An interval between use of medicine "Meralis ^® Intensiv" has to make not less than 6 hours.

Before the first application several vypryskivaniye in air (4 times) for achievement of uniformity of a dose. The bottle needs to be held in vertical position. If means is not used within several days (more than 6 days), it is necessary to make two vyprysk of spray in air to reach a uniform dose.

After use the spraying device should be wiped carefully with a clean paper towel and to put a protective cap into place.

to minimize risk of spread of an infection, medicine it should not be used more than one person.

7 days. Long-term treatment by xylomethazolinum a hydrochloride can cause a rhinedema and increase in secretion that is caused by hypersensitivity of cages - "converse effect".

even if duration of treatment is less than 7 days.

.

One injection (about 140 mkl) medicine "Meralis ^® Intensiv" contains about 70 mkg of xylomethazolinum of a hydrochloride and 84 mkg a bromide ipratropiya.

Feature of application

Pregnant

there are Not enough data on use of medicine during pregnancy. Preclinical data are not enough for assessment of the impact of medicine on a pregnancy course, development of an embryo/fruit, childbirth and postnatal development. The potential risk for the person is unknown. Drug should not be used during pregnancy without emergency.

Data on penetration. Systemic action ipratropiya of bromide and xylomethazolinum of a hydrochloride low. Therefore influence on the baby who is on breastfeeding is improbable. It is necessary to estimate need of use of medicine "Meralis ^® Intensiv" for the woman, advantages of breastfeeding and potential risk to the baby. Exceeding the recommended dose is inadmissible.

Children

do not use Drug to children (aged up to 18 years) in connection with insufficiency of data.

Drivers

At use of medicine can arise visual disturbances (including illegibility of sight and expansion of pupils), dizziness and increased fatigue. Patsiyentov it is necessary to warn that at emergence of similar reactions it is necessary to avoid control of motor transport or work with mechanisms and not to participate in activity which can lead to threat for health or life.

At oral overdose or at excessive topical administration of xylomethazolinum of a hydrochloride such phenomena are possible

: severe dizziness, the increased perspiration, sharp decrease in body temperature, a headache, bradycardia, arterial hypertension, respiratory depression, a coma and spasms. After arterial hypertension the arterial hypotension can develop. Children are more sensitive to toxicity, than adults. Symptomatic treatment.

a bromide ipratropiya the sharp overdose is improbable

At excessive intranasal application because of very insignificant absorption of medicine in blood at oral and intranasal administration, but such symptoms can develop: dryness in a mouth, accommodation difficulty, tachycardia. Symptomatic treatment.

Considerable overdose can cause anticholinergic symptoms from the central nervous system, including hallucinations for which elimination appoint cholinesterase inhibitors. The appropriate supporting measures are necessary for all persons with suspicion on overdose; emergency symptomatic treatment under observation of the doctor is appointed if necessary. It is necessary to watch the patient within not less than 6 hours. In case of heavy overdose with cardiac arrest the resuscitation events need to be held within not less than 1 hour.

Side effects

Most frequent side effects are nasal bleeding (14.8%) and dryness in a nose (11.3%).

Storage conditions

does not demand special storage conditions. To store out of children's reach.

Expiration date - 3 years.