Edoksakord of the tab. of p/o of 30 mg No. 30

Edoksakord – antitrombotichesky means. Direct inhibitor of a factor Ha for prevention of a stroke and a system embolism at adult patients with not valve fibrillation of auricles (NVFA) and one or several risk factors, such as stagnant heart failure, arterial hypertension, diabetes, stroke or tranzitorny ischemic attack (TI5).

For treatment of the deep vein thrombosis (DVT) and a pulmonary embolism (TELA) and also prevention of a recurrence of TGV and TELA at adults.

Structure

• 1 tablet contains edoksaban (in the form of monohydrate tosylate) 30 mg;
• other components: mannitol (E 421); prezhelatinizirovanny starch; krospovidon; hydroxypropyl cellulose; magnesium stearate;
• cover: Opadry II Pink 32F240010: gipromeloz (hydroksipropilmetiltsellyuloz); lactose, monohydrate; polyethyleneglycol (macrogoal); titan of dioxide (E 171); ferrous oxide red (E 172);

Contraindication

Hypersensitivity to active ingredient or to any excipient of medicine.

Clinically significant active bleeding.

Disease of a liver, followed by a coagulopathy and clinically essential risk of bleeding.

Route of administration

Prevention of a stroke and system embolism - the recommended dose makes 60 mg of an edoksaban of 1 times a day.

for a long time.

Treatment of TGV and TELA and also prevention of a recurrence of TGV and TELA (VTE) - the recommended dose makes 60 mg of an edoksaban of 1 times a day after primary parenteral use of anticoagulant within not less than 5 days. It is not necessary to apply at the same time edoksaban and parenteral anticoagulant.

Feature of use

Risk of developing bleeding

Edoksaban increases risk of bleeding and can cause heavy, potentially life-threatening bleedings. As well as other anticoagulants, it is recommended to apply with care edoksaban to patients at the states which are followed by the increased risk of bleeding. In case of serious bleeding the use of medicament should be stopped.

Pregnant

Medicine Edoksakord it is contraindicated to use during pregnancy.

by

.

Drivers

Medicine Edoksakord does not influence or almost does not influence speed of response at control of motor transport or other mechanisms.

Overdose of an edoksaban can lead

to bleeding. Experience of cases of overdose is very limited.

Side effects

from blood and lymphatic system: anemia, thrombocytopenia.

from the immune system: anaphylactic reactions, allergic hypostasis, hypersensitivity.

from nervous system: dizziness, headaches, intracraneal hemorrhage, subarachnoidal hemorrhage.

from organs of sight: eye hemorrhage, hemorrhages in a conjunctiva/sclera.

from heart: hemorrhage in a pericardium cavity.

to Store

in original packing at a temperature not above 25 °C.

to Store

out of children's reach.